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My experience is that wearing a mask doesn't stop the reactions from happening. I also do not get relief from using benedryl if it reaches a full blown athsma attack. I have found for me that the liquid benedryl (children's) gets in my system much faster than the pills. Unfortunately a bottle does not last long when used for adult doses.
Plus it is not a sin to get up and walk out or miss mass due to health reasons.
I guess I am less concerned about it being a sin than my actually missing the message from the service. So often when I am visiting a different Catholic Church I find the Holy Spirit has led me to that particular church. I plan to check before the service starts to see if there is a cry room in case I need it.
We have had several get up and leave because of Adoration benediction---if they are a visitor, they don't know we have benediction right before Mass on the third Saturday of the month. Regular attendees stay in the cry room, which has glassed out front and a closed door, or wait in the front hall until the benediction concludes. It is an issue at our Church. Prior priests used to use floral and other oddly scented incenses; the standard is now Frankincense and Myrrh. I almost think we should post a sign when incense is prescribed so people can sit in the cry room. No one with noisy children really sits there anyway. . . .